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There are several matches for 'DNA helicase II'.
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10068 matches
showing page 1 of 504
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organism
protein
1)
Escherichia coli K12
uvrD -
DNA
-dependent ATPase I and
helicase
II
; A
helicase
with
DNA
-dependent ATPase activity. Unwinds
DNA
duplexes with 3' to 5' polarity with respect to the bound strand. Initiates unwinding more efficiently from a nicked substrate than ds duplex
DNA
. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair, and probably also in repair of alkylated
DNA
(Probable).
[a.k.a. AAC76816.1, b3813, 2IS4,
DNA helicase II
]
2)
Homo sapiens
ERCC2 - General transcription and
DNA
repair factor IIH
helicase
subunit XPD; ATP-dependent 5'-3'
DNA
helicase
, component of the general transcription and
DNA
repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged
DNA
and, when complexed to CAK, in RNA transcription by RNA polymerase
II
. In NER, TFIIH acts by opening
DNA
around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new
DNA
fragment. The ATP-dependent
helicase
activity of XPD/ERCC2 is required for
DNA
opening. I [...]
[a.k.a. X52222, R-HSA-162587, OMIM:126340]
3)
Homo sapiens
XRCC6 - X-ray repair cross-complementing protein 6; Single-stranded
DNA
-dependent ATP-dependent
helicase
. Has a role in chromosome translocation. The
DNA
helicase
II
complex binds preferentially to fork-like ends of double-stranded
DNA
in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to
DNA
may be mediated by XRCC6. Involved in
DNA
non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the
DNA
-dependent protein kinase complex
DNA
-PK by increasing the affinity of the catalytic s [...]
[a.k.a. R-HSA-162587, ENST00000359308.8, HGNC:4055]
4)
Homo sapiens
XRCC5 - X-ray repair cross-complementing protein 5; Single-stranded
DNA
-dependent ATP-dependent
helicase
. Has a role in chromosome translocation. The
DNA
helicase
II
complex binds preferentially to fork-like ends of double-stranded
DNA
in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to
DNA
may be mediated by XRCC6. Involved in
DNA
non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the
DNA
-dependent protein kinase complex
DNA
-PK by increasing the affinity of the catalytic s [...]
[a.k.a. R-HSA-162587, NM_021141.3, ENST00000451695]
5)
Homo sapiens
ERCC3 - General transcription and
DNA
repair factor IIH
helicase
subunit XPB; ATP-dependent 3'-5'
DNA
helicase
, component of the general transcription and
DNA
repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged
DNA
and, when complexed to CAK, in RNA transcription by RNA polymerase
II
. In NER, TFIIH acts by opening
DNA
around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new
DNA
fragment. The ATPase activity of XPB/ERCC3, but not its
helicase
activity, is required fo [...]
[a.k.a. R-HSA-162587, ENST00000645467.1, R-HSA-6781823]
6)
Homo sapiens
RECQL5 - ATP-dependent
DNA
helicase
Q5; Isoform beta is a
DNA
helicase
that plays an important role in
DNA
replication, transcription and repair. Inhibits elongation of stalled transcripts at
DNA
damage sites by binding to the RNA polymerase
II
subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient
DNA
repair, including repair of inter-strand cross-links. Stimulates
DNA
decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
[a.k.a. ENST00000443199, RECQ5_HUMAN, NP_001003715.1]
7)
Homo sapiens
IGHMBP2 -
DNA
-binding protein SMUBP-2; 5' to 3'
helicase
that unwinds RNA and
DNA
duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin
II
gene RIPE3B enhancer region. May be involved in translation (By similarity).
DNA
-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch regio [...]
[a.k.a. XM_011544994, Glial factor 1, XP_016873160.1]
8)
Homo sapiens
CHD1 - Chromodomain-
helicase
-
DNA
-binding protein 1; ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase
II
transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively
DNA
replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated wit [...]
[a.k.a. OTTHUMG00000162744, 4NW2, HGNC:1915]
9)
Homo sapiens
GTF2F2 - General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase
II
and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent
DNA
-
helicase
activity.
[a.k.a. general transcription factor IIF subunit 2, R-HSA-162587, R-HSA-73776]
10)
Homo sapiens
SETX - Probable
helicase
senataxin; Probable RNA/DNA
helicase
involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase
II
(Pol
II
) binding to chromatin and through its interaction with proteins involved in transcription. Contributes to the mRNA splicing efficiency and splice site selection. Required for the resolution of R-loop RNA-
DNA
hybrid formation at G- rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA [...]
[a.k.a. ENSP00000361242, XM_011518404.3, SETX_HUMAN]
11)
Mus musculus
Ercc2 - General transcription and
DNA
repair factor IIH
helicase
subunit XPD; ATP-dependent 5'-3'
DNA
helicase
, component of the general transcription and
DNA
repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged
DNA
and, when complexed to CAK, in RNA transcription by RNA polymerase
II
. In NER, TFIIH acts by opening
DNA
around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new
DNA
fragment. The ATP-dependent
helicase
activity of XPD/ERCC2 is required for
DNA
opening. I [...]
[a.k.a. RCO015, AK082761, R-MMU-5696398]
12)
Mus musculus
Recql5 - ATP-dependent
DNA
helicase
Q5;
DNA
helicase
that plays an important role in
DNA
replication, transcription and repair. Inhibits elongation of stalled transcripts at
DNA
damage sites by binding to the RNA polymerase
II
subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient
DNA
repair, including repair of inter-strand cross-links. Stimulates
DNA
decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination (By similarity). Belongs to the helica [...]
[a.k.a. ENSMUST00000021097.9, DNA helicase, RecQ-like type 5, XP_006532421.1]
13)
Mus musculus
Xrcc5 - X-ray repair cross-complementing protein 5; Single-stranded
DNA
-dependent ATP-dependent
helicase
. Has a role in chromosome translocation. The
DNA
helicase
II
complex binds preferentially to fork-like ends of double-stranded
DNA
in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to
DNA
may be mediated by XRCC6. Involved in
DNA
non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the
DNA
-dependent protein kinase complex
DNA
-PK by increasing the affinity of the catalytic s [...]
[a.k.a. Ku86, MGI:104517, 22596]
14)
Mus musculus
Xrcc6 - X-ray repair cross-complementing protein 6; Single-stranded
DNA
-dependent ATP-dependent
helicase
. Has a role in chromosome translocation. The
DNA
helicase
II
complex binds preferentially to fork-like ends of double-stranded
DNA
in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to
DNA
may be mediated by XRCC6. Involved in
DNA
non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the
DNA
-dependent protein kinase complex
DNA
-PK by increasing the affinity of the catalytic s [...]
[a.k.a. ENSMUST00000170907.1, MGI:95606, Xrcc6-206]
15)
Mus musculus
Ercc3 - General transcription and
DNA
repair factor IIH
helicase
subunit XPB; ATP-dependent 3'-5'
DNA
helicase
, component of the general transcription and
DNA
repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged
DNA
and, when complexed to CAK, in RNA transcription by RNA polymerase
II
. In NER, TFIIH acts by opening
DNA
around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new
DNA
fragment. The ATPase activity of XPB/ERCC3, but not its
helicase
activity, is required fo [...]
[a.k.a. XM_006525636.2, R-MMU-5696398, DNA excision repair protein ERCC-3]
16)
Mus musculus
Ighmbp2 -
DNA
-binding protein SMUBP-2; 5' to 3'
helicase
that unwinds RNA and
DNA
duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin
II
gene RIPE3B enhancer region (By similarity). May be involved in translation.
DNA
-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch regio [...]
[a.k.a. ENSMUST00000025751.9, Smbp2, Smbp-2]
17)
Mus musculus
Chd1 - Chromodomain-
helicase
-
DNA
-binding protein 1; ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase
II
transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively
DNA
replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Required for the bridg [...]
[a.k.a. ENSMUSG00000023852, AW555109, ENSMUSP00000024620]
18)
Mus musculus
Gtf2f2 - General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase
II
and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent
DNA
-
helicase
activity (By similarity).
[a.k.a. 68705, R-MMU-72203, R-MMU-8939211]
19)
Mus musculus
Setx - Probable
helicase
senataxin; Probable RNA/DNA
helicase
involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase
II
(Pol
II
) binding to chromatin and through its interaction with proteins involved in transcription. Contributes to the mRNA splicing efficiency and splice site selection. Required for the resolution of R-loop RNA-
DNA
hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA a [...]
[a.k.a. AL845267, ENSMUSP00000051492, XM_006498079]
20)
Drosophila melanogaster
hay - General transcription and
DNA
repair factor IIH
helicase
subunit XPB; ATP-dependent 3'-5'
DNA
helicase
, component of the general transcription and
DNA
repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged
DNA
and, when complexed to CAK, in RNA transcription by RNA polymerase
II
. In NER, TFIIH acts by opening
DNA
around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new
DNA
fragment. The ATPase activity of haywire/XPB/ERCC3, but not its
helicase
activity, is req [...]
[a.k.a. FBgn0001179, hay-PA, hay-PB]
10068 matches
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